1.
Chinese Journal of Gastroenterology
;
(12): 563-566, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-478018
ABSTRACT
Liver fibrosis is a repair response to chronic liver injury caused by liver metabolic disorders due to many injury factors. Hepatic stellate cell(HSC)activation and proliferation play an important role in the pathogenesis of liver fibrosis. In recent years,studies showed that microRNAs(miRNA)are involved in signal transduction pathways related with HSC activation and proliferation. This article reviewed the role of miRNA in regulation of HSC biological behavior in liver fibrogenesis.